Cause of this disease is rapid or continued over time reduction a concentration of dissolved oxygen in the water below a limit value. This value depends on environmental conditions and fish species. The fish quickly die (within twenty-four hours) after exceeded the limit value.
The sources of oxygen in water are atmospheric air and photosynthesis. Oxygen diffusion from atmosphere happens only on the contact border of two environments. In other words, oxygen concentration reduces with the depth. We need remember that much less oxygen penetrates through standing water compared to rippling water. Water waving causes increase the surface diffusion and then we have more oxygen in the water. The amount of dissolved oxygen in the water depends on temperature and pressure. This amount decreases with increasing temperature. The amount of released oxygen by plants (in photosynthesis) is proportional to their ability to conversion of carbon dioxide and water into other compounds (so-called biological assimilation).
When we configure our aquarium (when we choose equipment, amount and kind of plants, fish, etc.) we should bear in mind that the oxygen balance in aquarium (emission-absorption) was always positive with with advantage for emission. Decomposers (bacteria decomposing dead organic matter) and unlit plants consume the most oxygen in the aquarium.
We need eliminate main cause of disease occurrence and we need increase water aeration when we have the initial stage of this illness (no fish died yet). Otherwise, when first fish start to die we transfer all fish to a separate aquarium (with properly prepared and well oxygenated water). The fish should rally after a few hours when permanent damage hasn't occurred. Anyway the immune system of the fish is weakened, so we should use adequate vitamin preparations and water treatment conditioners (e.g. Tetra AquaSafe, Sera Aquatan, JBL Atvitol, etc.). We eliminate main causes of disease occurrence in the general tank in this same time. We transfer back the fish to the general aquarium when the situation was brought under control.